Cannabidiol or CBD as it is commonly abbreviated, is one of the most prevalent Cannabinoids found within the Cannabis plant and it's various subspecies. It is one of around 111 odd cannabinoids currently known to exist. CBD has garnered a lot of interest over the last several years, as research both old and new seems to point to many amazing applications for this substance, as well as the flood of anecdotal evidence currently being presented by those that have been using CBD for various issues over the last several years. CBD is considered to be safe after some 40 years of study in countries such as Israel, with no known adverse side effects to humans.
CBD concentrations are more prominent in hemp and Ruderalis strains of Cannabis, as aggressive hybridization of drug strains of marijuana have resulted in CBD genetics being selected against in favor of high THC cultivars. As a result, most marijuana strains today have only a fraction of the CBD that cannabis plants typically produced before indoor hybridization occurred. With the new focus on CBD over the last decade or so, growers have begun to mix medical marijuana strains with hemp and ruderalis strains to re-introduce the recessive genetics for high CBD production back into the cannabis gene pool.
Unfortunately, we cannot say or share what we know, think, hope or have even seen/observed CBD actually do either personally or anecdotally, due to FDA regulations regarding health claims on nutritional supplements. Though we do not sell hemp oils ourselves, we link back to companies that do as a resource for folks, and we respect the much needed rules the FDA implements on the supplement industry and do not wish to cause any problems by extension for the merchants we highlight and link to, as they must abide by these guidelines. You can see the type of language the FDA precludes in the latest batch of warning letters issued to CBD companies in 2016 for medical "claims", and why the FDA is standing up for a pharmaceutical company by the name of GW Pharma, that wants to lock down all access to CBD other than pharmaceutical for obvious financial reasons. The hemp extract industry is actively pointing out the other side of this coin, and the inconsistencies with honoring the GW IND with regard to hemp oil extracts in particular, which differ from marijuana extracts, and have been in the food supply long before GW filed their IND for Cannabidiol. You can see the immediate response to the latest batch of FDA warning letters by leading hemp oil industry manufacturer/supplier CannaVest here.
This new breeding has resulted in an exciting new range of cannabis displaying these recessive genetics for CBD production, some of which are still considered marijuana under law, while others have low enough THC present to qualify for industrial hemp status. Examples of some of these CBD Rich strains that have gained attention over the last decade are strains such as: Cannatonic (kind of the grandfather of many high CBD plants), ACDC, Sour Tsunami, Harlequin, Dance Hall, R4, Charlotte's Web and Avidekel from Israel. Charlotte's Web is low enough in THC concentration that it may now be called a hemp plant under Colorado state law. Federally, this would still be considered to be a marijuana plant if grown on U.S. soil as hemp and marijuana are considered to be the same plant under the Controlled Substances Act, where most of the countries the United States currently imports hemp products from, use the defining line of .3% THC or lower for commercial hemp designation. CBD Rich Hemp Oil is not to be confused with common hempseed oils sold by popular brands such as Nutiva Hemp oil. They are essentially just superfoods, and a very good source of healthy omega fats.
No. CBD is generally described as being non-psychoactive, and it is not what is referred to as a CB1 receptor agonist like its cousin THC, the primary psychoactive constituent in Marijuana.
Somnolence or sleepiness is the most common reported side effect of high doses of CBD. There has been no observed toxicity found with CBD in decades of research in countries that conduct cannabis research such as Israel, the home of Dr. Raphael Mechoulam whom first described and isolated these substances some 50 years ago. Issues such as bowel disturbances and stomach upset can sometimes be attributed to other natural constituents of less filtered cannabis oils such as chlorophyll that a small % of people may be sensitive to.
One important side effect of CBD that may need to be accounted for, it that CBD can reduce the production of a key enzyme produced in the liver that is active in breaking down many modern pharmaceutical preparations. If using CBD in conjunction with traditional pharmaceuticals, it may be necessary to watch blood levels of the other medications to ensure proper absorption is being achieved with the diminished enzyme activity.
Yes. Researches working under the employment of the federal government of the United States secured a patent on CBD for its promise as a neuroprotective and antioxidant in 1999. Since these researches were employed at the time by the federal government, the government now holds the patent ownership rights. You can view this patent here.
CBD may be extracted from cannabis plants by many different methods and techniques, most involving dissolving the cannabinoids into a solvent such as various alcohols or butane that are then purged and removed during the oil making process. A newer more expensive technology has caught on in the Cannabis industry due to its excellent safety though that does not rely on these harsher solvent based methods, and that is called Super Critical CO2 Extraction. Most large manufacturers of High CBD Oil base are using this clean technology currently eliminating potentially harmful solvents from the process of making Cannabis oil altogether. Most folks that have fortunate access to high CBD strains of cannabis and choose to make cannabis oil themselves, make their own oils at home with simple butter infusions or 190 proof alcohol extractions. There are many guides that may be found on YouTube that show how to safely make both cannabutter and basic cannabis oils using 190 proof alcohol for those that wish to experiment with making their own pure CBD oil at home.
Hemp based CBD oils may be purchased from dozens of merchants online found on websites such as ours and they are popping up more and more in brick and mortar alternative health food stores. Amazon used to stock a good selection but have since removed any if all hemp oils that are advertised as "CBD oil". There are a few brands selling "hemp extract" on Amazon these days, but most have the just-pitched-a-tent feel to them. There are at times a handful of reputable brands listed on Amazon, but it is hit or miss from month to month as Amazon frequently removes the products, despite having sold CBD and hemp extracts for the last 3 years. Some countries such as Brazil and recently Mexico, offer CBD oils such as RSHO on a national level now by doctors prescription. In the U.S. the best access to CBD remains to be in the states that have legalized either the medicinal or recreational use of marijuana in terms of having more flexibility in crossing over the line of being a hemp oil or a marijuana oil, where some folks may need a little more THC in their cannabis oils. Folks in these states can choose both hemp oils and marijuana oils.
CBD oils may be used in a multitude of ways. If one does not mind the taste, they can simply be taken orally. Oral doses will take one to two hours to reach peak blood levels. If one finds the taste offensive, they may be mixed with other fatty or oily substances such as butter, coconut oil or peanut butter to both help cleanse the palette and aid in absorption by the body. Bear in mind that as much as 80 to 85% of an oral dose may be lost to first pass metabolism in the liver. A better approach is to take cannabis oils sublingually, by holding them under the tongue or smearing thick oil on the back of the teeth. A thick oil may be applied to a toothpick that may then be held under the tongue as a practical sublingual application. This method of administration will bypass first pass metabolism and allow the body to absorb the CBD without the liver acting as a filter.
CBD oils may also be applied topically, and this, like sublingual administration, will eliminate losses from first pass metabolism. Another super effective means of delivery is to either purchase or make your own CBD suppositories that may be taken rectally or vaginally. This can have the added benefit of putting things directly where needed when dealing with digestive issues.
CBD may also be smoked, dabbed or vaped, which is often the preferred method of delivery for those seeking relief from breakthrough issues that need fast uptake time and immediate onset. It takes around 7 seconds for an inhaled dose of cannabinoids to hit the brain vs. a couple of hours with an oral dose. Many companies produce vape oil blends for use with various commercial vaporizers on the market. We suggest buying the ones with the least amount of flavoring and additives and recommend a glycerin base over the commonly used carrier agent propylene glycol, which many may be sensitive too. This is the same carrier agent used in eciggs to carry the nicotine and provide the right consistency for the vape pens. Our recommendation is to buy a very high end vaporizer and pure, unadulterated CBD vape oil. These are challenging to find at the moment. Those that wish to dab, should ensure the oil is dabbable and free of waxes to prevent the risk of developing lipoid pneumonia over long term use.
CBD may be taken in very high doses, so it will be up to the individual to find their own thresholds of activity. Cannabis oils in general are trial and error, both in terms of finding the right blend of oil, and the effective dose. Folks turning to cannabis should be ready for this and anticipate some experimentation and trial and error. It may be necessary to purchase several oils before finding one blend that happens to really click with the individuals body or specific issue.
The main Cannabinoid that most folks are acquainted with is Delta 9 Tetrahydrocannabinol or THC, the Cannabinoid most identified with giving Cannabis its characteristic effect. And until very recently, THC was really the only metric that Cannabis was judged and bred by, in terms of its chemical composition.
Breeders historically have bred for higher THC content, as that is what drives the recreational side of cannabis use to some extent. While the effects of any given strain have to do with its Cannabinoid profile as a whole—that is to say, the sum of the various Cannabiniods and the various concentrations of the various Cannabiniods present— THC has long been the focus of what little Cannabis study there has been and the particular substance that many of the laws are based around.
While historically, most of the focus on Cannabis has been on THC, there has been some research done on the plethora of other Cannabiniods present in Cannabis, and one of these Cannabiniods that stands out in particular is Canabidiol (CBD) in terms of it's seemingly profound ability to impact health. We are learning more every day about how these substances interact with our bodies own Endocannabiniod system and how they can work to promote balance and harmony in the body.
The Endocannabiniod system refers to a network of receptors and the neurotransmitters first described in the late 80' and early 90's found in the bodies of all vertebrate life going back some 500 million years. It is perhaps one of the most important systems involved with basic health maintenance in the body. Your body produces its own endocannabiniods, and they bind to these receptor sites occurring all over the body- in the brain, the immune system, the glands, organs, etc- and have many implications in body functions such as: Pain sensation, appetite, memory, stress response, immune function, thermoregulation, reproduction, sleep, and many others. The neurotransmitter Anandamide (Sanskrit for bliss) first described in 1992, is in many ways your bodies own endogenously produced THC. Interestingly, Anandamide has also been found in another substance associated with joyous human feelings, and that would be chocolate!
The endocannabinoid system as we currently understand it, is made up of primarily 2 receptor sites, the CB1 and CB2 receptor sites, as well as other lesser understood sites and the substances such as endo and phyto-cannabinoids that bind to them. This system of neurotransmitters is unique in the body in that it is the only system we know of that provides what is termed retrograde feedback. Typically, neurotransmitters function as either agonist or antagonists on particular receptor sites in the body producing either and up or down regulation in function across that particular receptor site.
Cannabinoids by contrast, are able to form a feedback loop on these connections and regulate activity based on what the body needs for balance by either up or down regulating activity based on feedback from the system. This is fairly profound. Most pharma is designed to either up regulate or down regulate neurotransmitter activity, often with long term damage to the very receptor sites in question. The reason Cannabis Oil benefits sooo many people, is that we all share an endocannabinoid system!
Watch this short video for an absolutely awesome video representation of this system! One of the best descriptions I have seen as far as an animated reference.
Watch a detailed discussion of cannabis and the endocannabinoid system by Raphael Mechoulam, the man who discovered the active components in cannabis in the 60's as well as who's team first outlined and described the endocannabinoid system in the 1990s. You will not find a more knowledgeable source on Cannabis.
So we know that your body produces it's own endocannabiniods, and that the system that is in place to receive them is one that is responsible for many fundamental functions in the body. So where does cannabis come into the picture?
Pyytocannabiniods, are plant based cannabiniods appearing in plants such as Cannabis, Truffles, and also another well known herbal remedy, Echinacea. These Cannabiniods bind to the receptors in your Endocannabiniod system in the way that a key fits a lock. You have similar receptor/plant relationships with plants such as Opium where your body has its own opiate receptors, and produces its own opiates in the form of endorphins, which is what first led scientists to postulate that something such as the endocannabinoid system may also exist. It's almost like nature's grand scheme if you think about it, plants that are keyed to specific receptors in our bodies that effect the most profound conditions. The more we learn, the more we uncover the benefits of Medicinal Marijuana and medical Cannabis.
So that is where a substance like Cannabidiol (CBD) fits into the overall picture of good health. It is a naturally occurring substance that works in harmony with systems your body already runs on, not a piece of engineered pharma that shoehorns its way into your body and demands things be done the chemical way, leading to all sorts of additional illness and imbalance. Your body already runs on this stuff....its like water......you just have to help your body get it, if your thirsty. But how do you go about getting ahold of a substance derived from Cannabis if Cannabis is illegal?
There are primarily 3 recognized species of Cannabis. Cannabis Indica, Cannabis Sativa, and Cannabis Ruderalis. Indica and Sativas have historically been grown for recreational use, and have higher amounts of THC occurring in the floral product or bud as well as levels of other Cannabiniods but typically lack any CBD concentration. These strains share many qualities that make them desirable for recreational cultivation. Cannabis Ruderalis has increased levels of CBD and CBC, and has little to no naturally occurring THC. Hemp, refers internationally to Cannabis plants with less than .3% THC in them. In fact, hemp still grows wild throughout much of the U.S., a leftover from the days when Hemp growing was a huge part of American agriculture.
So while Cannabis Ruderalis and Hemp varieties typically lack THC, many of them have been found to be moderately or very high in CBD and other beneficial cannabinoids and terpenes. Most, if not all of the CBD Oil for Sale today is derived from plants that at least share hemp or Ruderalis genetics, both in medical marijuana states that use hemp hybrids, and the legal high CBD hemp oil sold nationally.
Since Hemp and its products are considered to fall into what are termed "hemp finishing products", there are no laws against CBD oil derived from imported industrial Hemp oil. More legal information is posted on our homepage here as well as our detailed FAQ page. We know that there is mounting evidence as to the efficacy of CBD with a host of ailments, but it remains tentatively out of reach for much of the country due to our laws regarding Medicinal Marijuana and Cannabis. Until last year, 2014, you could not grow Hemp legally in the United States, but you could go into a clothing store and buy a shirt made out of 100% Hemp fiber. In much the same way, you are now able to gain access to CBD oils and products derived from CBD Rich Hemp oil.
The products featured on this website are made from this process, using Hemp oil that is high in CBD but legally devoid of THC. Many of the Hemp varieties grown for industry in Europe produce reasonably decent levels of CBD. Currently, this Hemp must be bought from overseas, but now that we will have domestic Hemp growing in the U.S. for the first time in 80 years, this equation will change dramatically as the first crops of domestic Hemp are brought to market this year (2015) and next. Companies such as the ones featured on this website will be able to source domestic Hemp if they desire in the very near future, and Hemp that was grown specifically for high CBD levels, as opposed to industrial Hemp that just happen to have decent levels of CBD. Some of the biggest names in the CBD oil industry such as CannaVest and the Stanley Brothers Social Enterprises, are at already at work in states like Kentucky that have secured DEA permitted hemp seed to grow on U.S. soil.
Ideally, we will get to the point in the U.S. where medicines like Sativex – a CBD/THC medication already available in many countries, and currently undergoing trials in the U.S- will be approved and available for use, as some research seems to point to CBD being more effective in conjunction with THC and vice versa for certain conditions. Until that day comes, unless you live in a Medical Marijuana state and have a Medical Marijuana Card, with access to dispensaries, it will continue to be very difficult to gain access to many of theses products, if they contain THC. Products like the ones on this website offer the opportunity for people to try legitimate THC free CBD oil products for the first time, legally, in all parts of the county and offer a way thru the red tape the surrounds marijuana and the products derived from it. There are legal forms of Cannabis Oil for Sale available in the U.S. and around 40 other countries, they just must be derived from hemp and not marijuana.
Need more detailed information on cannabis oils? Check out our Ebook, The Cannabis Oil Companion: A comprehensive beginner's guide to hemp and marijuana oils available direct here on our website and from major retailers/formats such as Amazon Kindle and Barnes and Nobel Nook! Click on the book below to read a sample.
Still have questions? Browse the Cannabis Oil for Sale FAQ page!